Br-PEG7-Br
CAS No. 177987-04-1
Br-PEG7-Br ( —— )
产品货号. M26931 CAS No. 177987-04-1
Br-PEG7-Br 是一种基于 PEG 的 PROTAC 连接子,可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ¥113 | 有现货 |
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| 50MG | ¥161 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Br-PEG7-Br
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Br-PEG7-Br 是一种基于 PEG 的 PROTAC 连接子,可用于 PROTAC 的合成。
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产品描述Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体HBV| IL receptor
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研究领域——
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适应症——
化学信息
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CAS Number177987-04-1
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分子量496.233
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分子式C16H32Br2O7
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纯度>98% (HPLC)
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溶解度——
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SMILESBrCCOCCOCCOCCOCCOCCOCCOCCBr
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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γ-2-MSH (41-58), ami...
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line.
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