Azido-PEG12-NHS ester ( —— )

产品货号. M26894 CAS No. 2363756-50-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Azido-PEG12-NHS ester
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Azido-PEG12-NHS 酯是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。
产品描述

Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Ole1| Stearoyl-CoA Desaturase (SCD)
研究领域

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适应症

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1.Vincent BM, et al. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31.

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