Amino-PEG13-amine
CAS No. 1228119-65-0
Amino-PEG13-amine ( H2N-PEG13-CH2CH2NH2 )
产品货号. M26885 CAS No. 1228119-65-0
Amino-PEG13-amine 是一种基于 PEG 的 PROTAC 连接体,可用于 PROTAC 的合成。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ¥103 | 有现货 |
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| 10MG | ¥130 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Amino-PEG13-amine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Amino-PEG13-amine 是一种基于 PEG 的 PROTAC 连接体,可用于 PROTAC 的合成。
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产品描述Amino-PEG13-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词H2N-PEG13-CH2CH2NH2
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通路Others
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靶点Other Targets
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受体CK2| Clk2/CK2
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研究领域——
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适应症——
化学信息
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CAS Number1228119-65-0
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分子量632.789
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分子式C28H60N2O13
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (158.03 mM)
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SMILESNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Wang Y, et, al. Discovery of 5-(3-Chlorophenylamino)benzo[ c][2,6]naphthyridine Derivatives as Highly Selective CK2 Inhibitors with Potent Cancer Cell Stemness Inhibition. J Med Chem. 2021 Apr 22;64(8):5082-5098.
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