Thiethylperazine dimaleate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Thiethylperazine dimaleate 是 D2 受体和 H1 受体的拮抗剂。

Thiethylperazine dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.(In Vitro):Thiethylperazine dimaleate dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.(In Vivo):In APP/PS1 mice, Thiethylperazine dimaleate (3 mg/kg; intramuscular injection) causes a significant reduction of Aβ42 levels.

Thiethylperazine could enhance the antibiotic (Vancomycin) activity at a concentration as low as 2 μg/mL. Thiethylperazine inhibits Vancomycin-sensitive E. faecalis ATCC 29212, Vancomycin-resistant E. faecalis ATCC 51299 and vancomycin-resistant E. faecalis (VREF) isolates with MIC values of 8 μg/mL, 16 μg/mL and 8 μg/mL, respectively.

Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days; young APP/PS1 mice) treatment significantly reduces Aβ42 levels in APP/PS1 mice. Animal Model:Young Aβ precursor protein (APPswe) and mutant presenilin-1 (PS1) (APP/PS1) mice Dosage:3 mg/kg Administration:Intramuscular injection; twice daily; for 30 days Result:Significantly reduced Aβ42 levels in APP/PS1 mice.

Toresten | Norzine | Thiethylperazine maleate

GPCR/G Protein

Dopamine Receptor

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1179-69-7

631.76

C30H37N3O8S2

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (197.86 mM)

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCSc1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1

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(-20℃)

With Ice Pack

≥ 2 years