Imirestat ( AL 1576 | Alcon 1576 | HOE 843 )

产品货号. M26715 CAS No. 89391-50-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Imirestat
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Imirestat 是一种醛糖还原酶抑制剂，可用于糖尿病研究。
产品描述

Imirestat is an aldose reductase inhibitor that can be used in diabetes research.(In Vivo):Administration of 1 mg/kg Imirestat increased nerve conduction velocity, however, had no effect on resistance to hypoxic conduction block or deficits in insulin-stimulated Uban-sensitive ATPase activity.
体外实验

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体内实验

Imirestat (1 mg/kg) improves nerve conduction velocity but is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity.
同义词

AL 1576 | Alcon 1576 | HOE 843
通路

Endocrinology/Hormones
靶点

Reductase
受体

SIRT1
研究领域

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适应症

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1.Napper AD, et al. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54.

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