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Fluorofenidone
CAS No. 848353-85-5
Fluorofenidone ( AKF-PD )
产品货号. M26688 CAS No. 848353-85-5
Fluorofenidone 部分通过 PI3K/Akt 信号通路抑制 NADPH 氧化酶和细胞外基质 (ECM) 沉积来减轻肾间质纤维化的进展。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥566 | 有现货 |
|
| 10MG | ￥941 | 有现货 |
|
| 25MG | ￥1832 | 有现货 |
|
| 50MG | ￥2669 | 有现货 |
|
| 100MG | ￥3519 | 有现货 |
|
| 200MG | ￥4743 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥620 | 有现货 |
|
生物学信息
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产品名称Fluorofenidone
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Fluorofenidone 部分通过 PI3K/Akt 信号通路抑制 NADPH 氧化酶和细胞外基质 (ECM) 沉积来减轻肾间质纤维化的进展。
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产品描述Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
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体外实验——
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体内实验——
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同义词AKF-PD
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number848353-85-5
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分子量203.216
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分子式C12H10FNO
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 140 mg/mL (688.94 mM)
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SMILESCc1ccc(=O)n(c1)-c1cccc(F)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.
产品手册
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