Caracemide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Caracemide 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。

Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.(In Vitro):Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site.(In Vivo):After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine.

Caracemide inactivates R1 by covalent modification at the substrate-binding site and has a toxic metabolite, methylisocyanate (MIC), in vivo.

The mercapturic acid derivative AMCC was identified in urine rats following administration to rats of a single i.p. dose (6.6 mg/kg) of caracemide (NSC-253272). .

NSC-253272

Others

Other Targets

Anti-infection| Bacterial

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81424-67-1

189.171

C6H11N3O4

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (528.63 mM)

CNC(=O)ON(C(C)=O)C(=O)NC

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(-20℃)

With Ice Pack

≥ 2 years