Src Inhibitor 3

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Src Inhibitor 3 是 c 端 Src 激酶的有效抑制剂（CSK HTRF 中的 IC50 <3 nM，Caliper 测定中的 IC50 <4 nM）。 Src Inhibitor 3 可增加 T 细胞受体信号传导诱导的 T 细胞增殖。

Src Inhibitor 3 is an effective inhibitor of c-terminal Src kinase (IC50 <3 nM in CSK HTRF, <4 nM in Caliper assay). Src Inhibitor 3 increases T cell proliferation induced by T cell receptor signaling.(In Vivo):Src Inhibitor 3 (oral) reduces inhibitory LCK phosphorylation in vivo and shows the ability to enhance T cell activation in response to antigen stimulation.

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Others

Other Targets

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2380027-49-4

671.13

C34H32ClFN8O4

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (149.00 mM)

COc1ccc2c(cnn2c1)C(=O)Nc1ccc(NC(=O)c2nn(C3CCN(CC3)C(=O)CC(C)(C)C#N)c3ccc(F)cc23)cc1Cl

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(-20℃)

With Ice Pack

≥ 2 years