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SGN-2FF
CAS No. 2089647-47-0
SGN-2FF ( —— )
产品货号. M26438 CAS No. 2089647-47-0
SGN-2FF 是一种口服岩藻糖基转移酶抑制剂，具有抗肿瘤活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1169 | 有现货 |
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| 10MG | ￥1891 | 有现货 |
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| 25MG | ￥3692 | 有现货 |
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| 50MG | ￥5273 | 有现货 |
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| 100MG | ￥6912 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥891 | 有现货 |
|
生物学信息
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产品名称SGN-2FF
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SGN-2FF 是一种口服岩藻糖基转移酶抑制剂，具有抗肿瘤活性。
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产品描述SGN-2FF is an oral fucosyltransferase inhibitor with antitumor activity.(In Vitro):SGN-2FF is a fucosylation inhibitor, SGN-2FF inhibits cellular fucosylation by depleting the fucosylation substrate GDP-fucose, and by direct inhibition of fucosyltransferases, and leads to the production of fucosylated glycoproteins including antibodies. SGN-2FF activates human T cells in an antigen-dependent manner.(In Vivo):In multiple mouse tumor models, SGN-2FF exhibits antitumor activity. SGN-2FF shows substantial tumor growth delay. SGN-2FF elevates the protective effect of a lymphoma vaccine in a syngeneic mouse model.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Telomerase
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研究领域——
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适应症——
化学信息
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CAS Number2089647-47-0
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分子量166.148
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分子式C6H11FO4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (300.93 mM)
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SMILESC[C@@H]1OC(O)[C@@H](F)[C@H](O)[C@@H]1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Quan Wang J, et al. Discovery of new chromen-4-one derivatives as telomerase inhibitors through regulating expression of dyskerin. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1199-1211.
产品手册
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