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Oxotremorine M iodide
CAS No. 3854-04-4
Oxotremorine M iodide ( Oxotremorine methiodide )
产品货号. M26353 CAS No. 3854-04-4
Oxotremorine M iodide 是一种有效的非选择性毒蕈碱乙酰胆碱受体 (mAChR) 激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥244 | 有现货 |
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| 10MG | ￥392 | 有现货 |
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| 25MG | ￥540 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥269 | 有现货 |
|
生物学信息
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产品名称Oxotremorine M iodide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Oxotremorine M iodide 是一种有效的非选择性毒蕈碱乙酰胆碱受体 (mAChR) 激动剂。
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产品描述Oxotremorine M iodide is a potent and non-selective agonist of muscarinic acetylcholine receptor (mAChR).(In Vitro):Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM).?Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively.?Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents.(In Vivo):In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens.
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体外实验Oxotremorine M iodide (0.1, 0.3, 1, 3, 10, 30 μM) inhibits KCNQ2/3 currents in the concentration-dependence. Oxotremorine M iodide elicits a robust phosphoinositide response characterized with an EC50 of 0.22 μM. Oxotremorine M iodide has EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively.
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体内实验Oxotremorine M iodide (0.5 mg/kg; s.c.) increases Ddopamine (DA) release in the medial prefrontal cortex (mPFC) and has no effect in the nucleus accumbens (NAC) in male sprague-dawley albino rats weighing 250-350 g.
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同义词Oxotremorine methiodide
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通路Others
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靶点Other Targets
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受体5-HT1| 5-HT2| 5-HT4
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研究领域——
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适应症——
化学信息
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CAS Number3854-04-4
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分子量322.19
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分子式C11H19IN2O
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (387.97 mM)
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SMILES[I-].C[N+](C)(C)CC#CCN1CCCC1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Cajanin
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