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LDC7559
CAS No. 2407782-01-6
LDC7559 ( —— )
产品货号. M26276 CAS No. 2407782-01-6
LDC7559 通过在晚期阻断中性粒细胞胞外陷阱 (NET) 来抑制gasdermin D (GSDMD)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1786 | 有现货 |
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| 10MG | ￥2822 | 有现货 |
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| 25MG | ￥4576 | 有现货 |
|
| 50MG | ￥6343 | 有现货 |
|
| 100MG | ￥8262 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1387 | 有现货 |
|
生物学信息
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产品名称LDC7559
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LDC7559 通过在晚期阻断中性粒细胞胞外陷阱 (NET) 来抑制gasdermin D (GSDMD)。
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产品描述LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.(In Vitro):LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体VHL
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研究领域——
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适应症——
化学信息
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CAS Number2407782-01-6
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分子量349.38
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分子式C20H19N3O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (286.22 mM)
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SMILESO=C(NC1=CC=C2C(OCC3=CC(=NN3C2)C=4C=CC=CC4OC)=C1)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.
产品手册
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