021-51111890
购物车（）
sales@molnova.cn
Gallopamil hydrochloride
CAS No. 16662-46-7
Gallopamil hydrochloride ( Methoxyverapamil hydrochloride )
产品货号. M26224 CAS No. 16662-46-7
Gallopamil HydroHClide 是苯烷基胺钙的拮抗剂。盐酸加洛帕米可用于抗心律失常和血管扩张研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥585 | 有现货 |
|
| 10MG | ￥937 | 有现货 |
|
| 25MG | ￥1925 | 有现货 |
|
| 50MG | ￥2762 | 有现货 |
|
| 100MG | ￥3987 | 有现货 |
|
| 200MG | ￥5625 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥774 | 有现货 |
|
生物学信息
-
产品名称Gallopamil hydrochloride
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Gallopamil HydroHClide 是苯烷基胺钙的拮抗剂。盐酸加洛帕米可用于抗心律失常和血管扩张研究。
-
产品描述Gallopamil hydrochloride is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.(In Vitro):Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. (In Vivo):In male Wistar rats, Gallopamil hydrochloride (0.2 mg/kg; i.v. for 5 min) markedly reduces ventricular tachycardia and totally prevents fibrillation. Gallopamil hydrochloride significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate.
-
体外实验——
-
体内实验Gallopamil hydrochloride (Methoxyverapamil hydrochloride; i.v.; 0.2 mg/kg; for 5 min) markedly reduces ventricular tachycardia (VT) and totally prevents fibrillation (VF). Gallopamil significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate. Animal Model:Male Wistar rats weighing 290-370 g Dosage:0.2 mg/kg Administration:i.v.; 5 min Result:Markedly reduced VT and totally prevented VF.
-
同义词Methoxyverapamil hydrochloride
-
通路GPCR/G Protein
-
靶点Calcium Channel
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number16662-46-7
-
分子量521.1
-
分子式C28H41ClN2O5
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 100 mg/mL (191.91 mM)
-
SMILESCl.COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Yu X, Chang J, Liu X, Pan W, Zhang A. Theoretical study on the formation mechanism of polychlorinated dibenzothiophenes/thianthrenes from 2-chlorothiophenol molecules. J Environ Sci (China). 2018 Apr;66:318-327.
