D-3263 hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

D-3263 盐酸盐是肠溶的、口服生物可利用的（瞬时受体潜在褪黑激素成员 8）TRPM8 激动剂。

D-3263 hydrochloride is enteric-coated, orally bioavailable (transient receptor potential melatonin member 8) TRPM8 agonist.(In Vitro):D-3263 hydrochloride binds and activates TRPM8, which may lead to increased entry of calcium and sodium; destruction of calcium and sodium homeostasis; induction of cell death in tumor cells expressing TRPM8. D-3263 hydrochloride may reduce the level of dihydrotestosterone (DHT), which may contribute to its inhibitory effect on prostate cancer and BPH.

D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH.?

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D3263 HCl salt | EC D-3263 HCl

Others

Other Targets

GnRHR

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1008763-54-9

409.96

C21H32ClN3O3

>98% (HPLC)

In Vitro:?DMSO : 140 mg/mL (341.51 mM)

Cl.COc1ccc2n(C(=O)[C@@H]3C[C@H](C)CC[C@H]3C(C)C)c(=O)n(CCN)c2c1

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(-20℃)

With Ice Pack

≥ 2 years