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CYP17-IN-1
CAS No. 2093317-51-0
CYP17-IN-1 ( —— )
产品货号. M26134 CAS No. 2093317-51-0
CYP17-IN-1 是一种有效的口服 CYP17 抑制剂，可抑制大鼠和人类的 CYP17，IC50 分别为 15.8 和 20.1 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1093 | 有现货 |
|
| 5MG | ￥1701 | 有现货 |
|
| 10MG | ￥2499 | 有现货 |
|
| 25MG | ￥3850 | 有现货 |
|
| 50MG | ￥5282 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CYP17-IN-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CYP17-IN-1 是一种有效的口服 CYP17 抑制剂，可抑制大鼠和人类的 CYP17，IC50 分别为 15.8 和 20.1 nM。
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产品描述CYP17-IN-1 is an effective oral CYP17 inhibitor that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.(In Vitro):The IC50 value of CYP17-IN-1 for CYP3A4 is 8.5 μM.(In Vivo):CYP17-IN-1 dose-dependently reduced plasma testosterone levels in Sprague-Dawley rats.
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体外实验CYP17-IN-1 (compound 9c) exhibits an IC50 value of 8.5 μM against CYP3A4.
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体内实验CYP17-IN-1 (compound 9c) reduces plasma testosterone level in a dose-dependent manner in Sprague-Dawley rats.
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同义词——
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通路Metabolic Enzyme/Protease
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靶点P450
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受体carbonic anhydrase
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研究领域——
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适应症——
化学信息
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CAS Number2093317-51-0
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分子量312.41
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分子式C18H17FN2S
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ccncc1CN1CCc2c(C1)sc1ccc(F)cc21
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Prete SD, et, al. Escherichia coli γ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1545-1554.
产品手册
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