Clocapramine dihydrochloride hydrate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Clocapramine Hydrochronic Hydrate 是 5-HT2A 和 D2 受体的拮抗剂。

Clocapramine hydrochloride hydrate is an antagonist of the 5-HT2A and D2 receptors.(In Vivo):Clocapramine shows the lowest potency for D2-occupancy in vivo . An in vivo receptor binding technique is used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D2 and frontal serotonin-5-HT2 receptors in a rat brain using more specific ligands. Clocapramine produces ratios of potency in occupying 5-HT2 versus D2 receptors that fall between these two groups (ED50s: 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2) .

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Clocapramine shows the lowest potency for D2-occupancy in vivo. An in vivo receptor binding technique is used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D2 and frontal serotonin-5-HT2 receptors in a rat brain using more specific ligands. Clocapramine produces ratios of potency in occupying 5-HT2 versus D2 receptors that fall between these two groups (ED50 of 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2).

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Others

Other Targets

Wnt

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60789-62-0

572.01

C28H41Cl3N4O2

>98% (HPLC)

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O.Cl.Cl.NC(=O)C1(CCN(CCCN2c3ccccc3CCc3ccc(Cl)cc23)CC1)N1CCCCC1

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(-20℃)

With Ice Pack

≥ 2 years