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CAY10595
CAS No. 916047-16-0
CAY10595 ( —— )
产品货号. M26090 CAS No. 916047-16-0
CAY10595 是 CRTh2 (DP2) 受体的拮抗剂，Ki 为 10 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1834 | 有现货 |
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| 10MG | ￥2670 | 有现货 |
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| 25MG | ￥4129 | 有现货 |
|
| 50MG | ￥5571 | 有现货 |
|
| 100MG | ￥7182 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CAY10595
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述CAY10595 是 CRTh2 (DP2) 受体的拮抗剂，Ki 为 10 nM。
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产品描述CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.(In Vivo):CAY10595 slightly delays the development of CIA and reduces IgG2a anti-CII levels without modification of the levels of IgG anti-CII.
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体外实验CAY10595 (compound 71) is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM.
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体内实验Administration of the DP2 antagonist CAY10595 slightly delays the development of CIA. Treatment with CAY10595 reduces IgG2a anti-CII levels without modification of IgG anti-CII levels.
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同义词——
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通路Cell Cycle/DNA Damage
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靶点GPR
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受体CK2| MELK| Mps1| NEK6
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研究领域——
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适应症——
化学信息
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CAS Number916047-16-0
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分子量451.23
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分子式C20H13Cl2FN2O5
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(O)CN1C(=O)C2(C(=O)N(C(=O)C2)CC3=CC(Cl)=CC=C3F)C4=CC(Cl)=CC=C41
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Colombo R, et al. Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res. 2010 Dec 15;70(24):10255-64.
