1-Methylxanthine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

1-甲基黄嘌呤是一种咖啡因衍生物。 1-甲基黄嘌呤是咖啡因和茶碱的人体必需尿代谢物（1,3-二甲基黄嘌呤，TP）。

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.(In Vitro):1-Methylxanthine exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine and theobromine, 3-Methylxanthine, and 1-methylxanthine do not occur naturally at high levels in plants. 1-Methylxanthine (3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.

1-Methylxanthine (1-MTX; 3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.1-Methylxanthine (1MX) exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine, TP, and theobromine, 3-Methylxanthine (3MX) and 1-methylxanthine do not occur naturally at high levels in plants.

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Proteasome/Ubiquitin

Endogenous Metabolite

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6136-37-4

166.14

C6H6N4O2

>98% (HPLC)

In Vitro:?DMSO : 10 mg/mL (60.19 mM)

Cn1c(=O)[nH]c2nc[nH]c2c1=O

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(-20℃)

With Ice Pack

≥ 2 years