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PF-04745637
CAS No. 1917294-46-2
PF-04745637 ( —— )
产品货号. M26002 CAS No. 1917294-46-2
PF-04745637 是一种有效的选择性 TRPA1 拮抗剂，IC50 为 17 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1131 | 有现货 |
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| 10MG | ￥1634 | 有现货 |
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| 25MG | ￥2744 | 有现货 |
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| 50MG | ￥3841 | 有现货 |
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| 100MG | ￥5031 | 有现货 |
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| 200MG | ￥6795 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1264 | 有现货 |
|
生物学信息
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产品名称PF-04745637
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述PF-04745637 是一种有效的选择性 TRPA1 拮抗剂，IC50 为 17 nM。
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产品描述PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM.(In Vivo):PF-04745637 (topically applied; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin.
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体外实验——
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体内实验Topically applied PF-04745637 (Compound 8; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin.
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点TRP/TRPV Channel
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受体Immunology/Inflammation related
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研究领域——
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适应症——
化学信息
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CAS Number1917294-46-2
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分子量509.01
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分子式C27H32ClF3N2O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (245.58 mM)
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SMILESOC1(CCN(CC1)C(CNC(=O)C1(CCCC1)c1ccc(Cl)cc1)Cc1ccccc1)C(F)(F)F
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers.Cancer Lett., 2002, 177(1):7-12.
