Arecoline ( —— )

产品货号. M25045 CAS No. 63-75-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Arecoline
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

槟榔碱是毒蕈碱和烟碱乙酰胆碱受体的激动剂。它以各种盐的形式用作神经节兴奋剂、拟副交感神经药和驱虫剂，特别是在兽医实践中。
产品描述

Arecoline is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice.
体外实验

Arecoline induces the generation of reactive oxygen species and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting the expression of p21/Cip1. Arecoline-induced epithelial cell death at higher concentrations is caused by oxidative trauma without eliciting apoptosis. Arecoline upregulates the expression of the following stress-responsive genes: hemeoxygenase-1; ferritin light chain; glucose-6-phosphate dehydrogenase; glutamatecysteine ligase catalytic subunit; and glutathione reductase.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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计算器

产品手册

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