15-Lipoxygenase Inhibitor 1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

15-Lipoxygenase Inhibitor 1 是 15-lipoxygenase 的选择性抑制剂。

15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate cancer.(In Vitro):4-MMPB has an IC50 of 69.6 μM for DPPH bleaching.4-MMPB exhibits cytotoxic activity on human PC-3 and HFF3 cell lines.4-MMPB (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells.

4-MMPB has an IC50 of 69.6 μM for DPPH bleaching.4-MMPB exhibits cytotoxic activity on human PC-3 and HFF3 cell lines.4-MMPB (41.48 μM; 72 hours) induces apoptosis and DNA damage in PC-3 Cells.Cell Viability Assay Cell Line:DU145 cells, PC-3 cells, HFF3 cells Concentration:9.57 μM, 19.94 μM, 39.88 μM, 79.77 μM,159.53 μM Incubation Time:24 hours, 48 hours, 72 hours Result:Inhibited cells viability (IC50=79.76 μM; 24 h, 51.05 μM; 48 h, 41.48 μM; 72 h for PC-3 cells, IC50=255.25 μM; 24 h, 130.81 μM; 48 h, 98.91 μM; 72 h for HFF3 cells).

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4-MMPB

Others

Other Targets

Others

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928853-86-5

313.4

C16H19N5S

>98% (HPLC)

DMSO:8mg/mL (25.52mM)

CC1=C2C(=NC(=N1)N3CCN(CC3)C)SC4=CC=CC=C4N2

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(-20℃)

With Ice Pack

≥ 2 years