Ziconotide Acetate (107452-89-1 free base)

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

齐考诺肽是一种镇痛剂，已用于治疗神经性和非神经性疼痛。齐考诺肽通过与位于伤害感受通路初级传入神经元末端的 N 型钙通道结合而发挥作用，从而减少突触传递，具有有效的抗伤害作用。

Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.

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Prialt

GPCR/G Protein

Calcium Channel

N-type calcium

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914451-03-8

2639.2

C102H172N36O32S7

>98% (HPLC)

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CC1C(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(CSSCC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NCC(=O)N1)CCCCN)CCCCN)N)C(=O)NC(C(=O)NCC(=O)NC(C(=O)N3)CO)C(C)O)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CO)CCCNC(=N)N)CC(C)C)CCSC)CC4=CC=C(C=C4)O)CC(=O)O)C(=O)N)CCCCN)CO)CCCNC(=N)N)CCCCN.CC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years