Raloxifene ( Pharoxifene | Raloxifenum | Keoxifene | LY-139481 )

产品货号. M24833 CAS No. 84449-90-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Raloxifene
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

雷洛昔芬是一种选择性雌激素受体调节剂。它对骨癌、乳腺癌和心血管疾病风险有影响。
产品描述

Raloxifene is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk.
体外实验

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体内实验

Raloxifene (4?mg/kg; intragastrically; daily for 13 weeks) significantly prevents bone loss in ovariectomized (OVX) rats. Animal Model:Female, 12-week-old, Wistar rats (OVX rats) Dosage:4?mg/kg Administration:Intragastrically; daily for 13 weeks Result:Significantly increased the levels of E2 in OVX rats and significantly decreased the levels of BGP.
同义词

Pharoxifene | Raloxifenum | Keoxifene | LY-139481
通路

Others
靶点

Other Targets
受体

SERM
研究领域

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适应症

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CAS Number

84449-90-1
分子量

473.58
分子式

C28H27NO4S
纯度

>98% (HPLC)
溶解度

DMSO:90 mg/mL (190.04 mM; Need ultrasonic)；Ethanol:9 mg/mL (19.00 mM; Need ultrasonic)
SMILES

Oc(cc1)ccc1-c1c(C(c(cc2)ccc2OCCN2CCCCC2)=O)c(ccc(O)c2)c2s1
化学全称

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