Anserine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

鹅丝氨酸是一种含有β-丙氨酸和组氨酸的二肽，存在于哺乳动物和鸟类的骨骼肌和大脑中。

Anserine is a dipeptide containing β-alanine and histidine, which can be found in the skeletal muscle and brain of mammals and birds.?Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents.?Anserine improves memory functions in Alzheimer's disease (AD)-model mice.

——

Anserine (drinking water at a concentration of 2.0?g/L (equivalent to 10?mg/mouse); for 8 weeks) completely recoveres the memory deficits, improves pericyte coverage on endothelial cells in the brain, and diminishes chronic glial neuroinflammatory reactions in AβPPswe/PSEN1dE9 Alzheimer's disease (AD) model mice over 18-months old.

L-Anserine

Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

——

——

584-85-0

240.26

C10H16N4O3

>98% (HPLC)

DMSO:Insoluble;Water:10 mM

O=C(O)[C@H](CC1=CN=CN1C)NC(CCN)=O

——

(-20℃)

With Ice Pack

≥ 2 years