Congo Red

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

刚果红是一种偶氮染料。它的结合被用作组织切片中淀粉样蛋白存在的诊断测试。

Congo Red is an azo dye. It binding been used as a diagnostic test for the presence of amyloid in tissue sections.

Congo Red histochemical stain may serve as a simple screening tool for investigating if the aggregates in mutant cells have misfolded β-pleated sheet secondary structures. Congo Red histochemical dye has the ability to bind specifically to crossed β-pleated sheet structures. Wild-type HSPB1 should maintain protein homeostasis by binding proteins in non-native conformations, thereby preventing substrate aggregation. The T139M mutant, however, fails in this function and results in an accumulation of misfolded proteins, which are targeted by Congo Red for intercalating between the β-pleated sheet structures. Congo Red histochemical stain may serve as a simple tool to investigate if the aggregates in mutant cells have misfolded β-pleated sheet secondary structures.

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Direct Red 28

Others

Other Targets

Others

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573-58-0

696.66

C32H22N6Na2O6S2

>98% (HPLC)

DMSO:100 mg/mL (143.54 mM;Need ultrasonic)

Nc(c1ccccc1c(S([O-])(=O)=O)c1)c1N=Nc(cc1)ccc1-c(cc1)ccc1N=Nc(cc(c1ccccc11)S([O-])(=O)=O)c1N.[Na+].[Na+]

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(-20℃)

With Ice Pack

≥ 2 years