021-51111890
购物车（）
sales@molnova.cn
Tocainide
CAS No. 41708-72-9
Tocainide ( —— )
产品货号. M24378 CAS No. 41708-72-9
托卡尼是钠通道阻滞剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥113 | 有现货 |
|
| 25MG | ￥166 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥185 | 有现货 |
|
生物学信息
-
产品名称Tocainide
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述托卡尼是钠通道阻滞剂。
-
产品描述Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.(In Vivo):Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity.
-
体外实验——
-
体内实验Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogs with coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity.
-
同义词——
-
通路Membrane Transporter/Ion Channel
-
靶点Sodium Channel
-
受体sodium channel
-
研究领域——
-
适应症——
化学信息
-
CAS Number41708-72-9
-
分子量192.13
-
分子式C11H16N2O
-
纯度>98% (HPLC)
-
溶解度DMSO:10 mM
-
SMILESCC(N)C(NC1=C(C)C=CC=C1C)=O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23.
产品手册
关联产品
-
GX-585
GX-585 is a sulfonamide analog that is a Nav 1.7 channel inhibitor with analgesic activity for the study of neuropathic pain and inflammation.
-
Ambroxol hydrochlori...
Ambroxol HCl 是神经元 Na+ 通道的有效抑制剂，抑制 TTX 抗性 Na+ 电流，IC50 为 35.2 μM，对于强直和相位阻滞，IC50 为 35.2 μM，IC50 为 22.5 μM。
-
GS967
GS967 是一种新型、有效、选择性的心脏晚钠电流 (late INa) 抑制剂。
