Lipofermata ( —— )

产品货号. M24217 CAS No. 297180-15-5

COA

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HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Lipofermata
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Lipofermata 是一种脂肪酸转运蛋白 (FATP) 抑制剂，可阻止脂质转运至黑色素瘤细胞并减少黑色素瘤的生长和侵袭。
产品描述

Lipofermata is a fatty acid transport protein (FATP) inhibitor that prevents lipid transport to melanoma cells and reduces melanoma growth and invasion.
体外实验

Lipofermata inhibits C1-BODIPY-C12 transport into C2C12, INS-1E, Caco-2 and HepG2 cells at comparable levels yielding sigmoidal dose-response curves with IC50s in the low micromolar range (IC50=2.74-39.34 μM).
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

FATP
研究领域

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适应症

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1.Zhang M,et al. Adipocyte-Derived Lipids Mediate Melanoma Progression via FATP Proteins. Cancer Discov. 2018 Aug;8(8):1006-1025.

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