Artemisone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Artemisone 是一种有效的半合成抗疟药，可抑制恶性疟原虫菌株（IC50：0.83 nM）。它也是 CMV 的有效抑制剂。

Artemisone is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.

Artemisone inhibits 3D7 and K1 P. falciparum, with IC50s of 0.88±0.59 and 1.23±0.64 nM, respectively.

Artemisone is effectve at inhibiting the parasitaemia in the P. berghei NY susceptible strain, with an ED50 of 9.62 mg/kg via subcutaneous route and 11.67 mg/kg via oral administration.Artemisone (3, 1, 0.3 and 0.1 mg/kg, s.c.) in combination with ohter antimalarials has enhanced effect against the chloroquine-resistant line P. yoelii NS

Artemifone | BAY 44-9585

Microbiology/Virology

Parasite

CMV|P. falciparum|Parasite

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255730-18-8

401.52

C19H31NO6S

>98% (HPLC)

DMSO:130 mg/mL (323.77 mM; Need ultrasonic)

C[C@H](CC[C@H]1[C@H]2C)[C@H](C3)[C@]11OO[C@@]3(C)CO[C@H]1O[C@H]2N(CC1)CCS1(=O)=O

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(-20℃)

With Ice Pack

≥ 2 years