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TRPV4 agonist-1
CAS No. 2314467-60-0
TRPV4 agonist-1 ( —— )
产品货号. M24057 CAS No. 2314467-60-0
TRPV4 agonist-1 是 TRPV4 的激动剂（EC50：在 hTRPV4 Ca2+ 测定中为 60 nM）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥9858 | 有现货 |
|
| 50MG | ￥12834 | 有现货 |
|
| 100MG | ￥15750 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TRPV4 agonist-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TRPV4 agonist-1 是 TRPV4 的激动剂（EC50：在 hTRPV4 Ca2+ 测定中为 60 nM）。
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产品描述TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).
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体外实验TRPV4 agonist-1 (Compound 36) exhibits significantly increased potency (ECmax: 20 nM in the SOX9 reporter assay). TRPV4 agonist-1 is inactive against TRPV1 channels.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体hTRPV4 Ca2+
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研究领域——
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适应症——
化学信息
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CAS Number2314467-60-0
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分子量484.93
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分子式C25H23ClF2N4O2
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C1N(C2=CC=C(OC3=CC=C(F)C=C3)C=C2)C(N4CCN(C)CC4)=NC5=C1C=CC=C5F.[H]Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Atobe M, et al. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Jan 28.
产品手册
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