4-P-PDOT

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

4-P-PDOT 是一种有效的、选择性的、亲和力的褪黑素受体 (MT2) 拮抗剂。

4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist.

Cell Viability Assay Cell Line:HT-29 and HeLa cells.Concentration:50 μM Incubation Time:30 min Result:Produced a negligible effect on cell viability induced by melatonin.

Animal Model:Klotho mutant mice treatment with Melatonin Dosage:0.5 mg/kg or 1.0 mg/kg Administration:Intravenous injection Result:Significantly reversed antioxidant effects mediated by Melatonin. Significantly reversed the changes in the levels of these GSH-related parameters. Significantly reversed the memory function of Melatonin-treated klotho mutant mice.

4-phenyl-2- propionamidotetralin

Others

Other Targets

MT2 receptor

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134865-74-0

279.38

C19H21NO

>98% (HPLC)

DMSO:41.67 mg/mL (149.15 mM; Need ultrasonic)

CCC(=O)NC1CC(C2=CC=CC=C2C1)C3=CC=CC=C3

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(-20℃)

With Ice Pack

≥ 2 years