Mito-TEMPO

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Mito-TEMPO 是一种靶向线粒体的超氧化物歧化酶模拟物。 Mito-TEMPO 具有超氧化物和烷基自由基清除特性。

Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.(In Vivo):Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.

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Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.

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Others

Other Targets

Mitochondrial Metabolism

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1334850-99-5

510.03

C29H35ClN2O2P

>98% (HPLC)

DMSO:125 mg/mL (245.08 mM; Need ultrasonic);H2O:60 mg/mL (117.64 mM; Need ultrasonic)

[O]N1C(C)(C)CC(NC(C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1(C)C.[Cl-]

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(-20℃)

With Ice Pack

≥ 2 years