Sodium metatungstate
CAS No. 12141-67-2
Sodium metatungstate ( Sodium polyoxotungstate | POM-1 )
产品货号. M23382 CAS No. 12141-67-2
Sodium metatungstate 是外核苷三磷酸二磷酸水解酶 (NTPDase) 的有效抑制剂(NTPDase 1、NTPDase 3 和 NTPDase 2 的 Ki 值分别为 2.58 μM、3.26 μM 和 28.8 μM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ¥242 | 有现货 |
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| 25MG | ¥375 | 有现货 |
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| 50MG | ¥543 | 有现货 |
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| 100MG | ¥774 | 有现货 |
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| 500MG | ¥1998 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥368 | 有现货 |
|
生物学信息
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产品名称Sodium metatungstate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Sodium metatungstate 是外核苷三磷酸二磷酸水解酶 (NTPDase) 的有效抑制剂(NTPDase 1、NTPDase 3 和 NTPDase 2 的 Ki 值分别为 2.58 μM、3.26 μM 和 28.8 μM)。
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产品描述Sodium metatungstate is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively).
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体外实验——
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体内实验Animal Model:Multiple myeloma (MM) mice developed by 3 weeks of injection of 5t33MM cells Dosage:5 mg/kg Administration:Intraperitoneal injection (i.p.)Result:Had significantly lower spleen weights, fewer tumor cells in the spleen as well as significantly lower monoclonal immunoglobulin component level in circulation.
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同义词Sodium polyoxotungstate | POM-1
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number12141-67-2
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分子量2869.03
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分子式H2Na6O40W12
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纯度>98% (HPLC)
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溶解度H2O: 48 mg/mL (16.07 mM; Need ultrasonic); DMSO: 48 mg/mL (16.07 mM; Need ultrasonic)
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Müller CE, et al. Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7.
产品手册
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