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ELOVL6-IN-1
CAS No. 1185736-98-4
ELOVL6-IN-1 ( —— )
产品货号. M23355 CAS No. 1185736-98-4
ELOVL6-IN-1 是一种有效的、口服活性的、选择性的 ELOVL6 抑制剂。 ELOVL6-IN-1 剂量依赖性地抑制小鼠 ELOVL6 活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥1188 | 有现货 |
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| 10MG | ￥1739 | 有现货 |
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| 25MG | ￥2688 | 有现货 |
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| 50MG | ￥3701 | 有现货 |
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| 100MG | ￥4833 | 有现货 |
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| 200MG | ￥6210 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1226 | 有现货 |
|
生物学信息
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产品名称ELOVL6-IN-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ELOVL6-IN-1 是一种有效的、口服活性的、选择性的 ELOVL6 抑制剂。 ELOVL6-IN-1 剂量依赖性地抑制小鼠 ELOVL6 活性。
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产品描述ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities, with an?IC50?value of 0.350 μM. ELOVL6-IN-1 inhibits?ELOVL6?in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体ELOVL6
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研究领域——
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适应症——
化学信息
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CAS Number1185736-98-4
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分子量495.49
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分子式C27H24F3N3O3
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纯度>98% (HPLC)
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溶解度DMSO:45 mg/mL?(90.82 mM;?Need ultrasonic)
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SMILESO=C1N(C2=CC=CC=C2)C3=C(C(C(C)(C)CC3)=O)C1(C4=C(C)NN(C5=CC=CC=C5)C4=O)C(F)(F)F
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shimamura K, et al. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool. J Pharmacol Exp Ther. 2009;330(1):249-256.
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