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SCH-37370
CAS No. 117796-52-8
SCH-37370 ( SCH 37370 | SCH37370 )
产品货号. M23344 CAS No. 117796-52-8
SCH-37370 是一种有效的口服活性血小板激活因子和组胺双重拮抗剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥751 | 有现货 |
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| 10MG | ￥1064 | 有现货 |
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| 25MG | ￥1748 | 有现货 |
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| 50MG | ￥2502 | 有现货 |
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| 100MG | ￥3312 | 有现货 |
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| 200MG | ￥4383 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥718 | 有现货 |
|
生物学信息
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产品名称SCH-37370
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SCH-37370 是一种有效的口服活性血小板激活因子和组胺双重拮抗剂。
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产品描述SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
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体外实验——
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体内实验——
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同义词SCH 37370 | SCH37370
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通路Others
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靶点Other Targets
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受体PAF
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研究领域——
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适应症——
化学信息
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CAS Number117796-52-8
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分子量352.86
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分子式C21H21ClN2O
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纯度>98% (HPLC)
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溶解度DMSO:Soluble
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SMILESCC(N(CC1)CCC1=C(c(cc1)c(CC2)cc1Cl)c1c2cccn1)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kaminski JJ, Carruthers NI, Wong SC, Chan TM, Billah MM, Tozzi S, McPhail AT. Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine. Bioorg Med Chem. 1999 Jul;7(7):1413-23. PubMed PMID: 10465415.
