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MitoBloCK-11?(MB-11)
CAS No. 413606-16-3
MitoBloCK-11?(MB-11) ( —— )
产品货号. M22985 CAS No. 413606-16-3
MitoBloCK-11 (MB-11) 是线粒体蛋白输入的小分子抑制剂，可能通过转运蛋白 Seo1 起作用，但不是 Tom70 或 Tom20；抑制含有疏水片段的前体蛋白，以特定方式在缺乏尿嘧啶的培养基中生长，并影响斑马鱼的发育。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥979 | 有现货 |
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| 10MG | ￥1501 | 有现货 |
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| 25MG | ￥2306 | 有现货 |
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| 50MG | ￥3181 | 有现货 |
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| 100MG | ￥4077 | 有现货 |
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| 200MG | ￥5499 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1121 | 有现货 |
|
生物学信息
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产品名称MitoBloCK-11?(MB-11)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MitoBloCK-11 (MB-11) 是线粒体蛋白输入的小分子抑制剂，可能通过转运蛋白 Seo1 起作用，但不是 Tom70 或 Tom20；抑制含有疏水片段的前体蛋白，以特定方式在缺乏尿嘧啶的培养基中生长，并影响斑马鱼的发育。
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产品描述MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20;?inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体mitochondrial protein import
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研究领域——
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适应症——
化学信息
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CAS Number413606-16-3
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分子量434.3
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分子式C17H12BrN3O4S?
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (287.85 mM)
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SMILESO=C(NN=CC1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Tremelimumab
Tremelimumab (Ticilimumab) 是一种完全人源化的单克隆抗体，对细胞毒性 T 淋巴细胞抗原 4 (CTLA-4) 具有特异性，可用于转移性黑色素瘤研究。
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Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating hormones from the anterior pituitary.Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS.
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Licoflavanone
Licoflavanone exhibits antioxidant and anti-inflammatory activities,it markedly decreases pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels.
