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MBCQ
CAS No. 150450-53-6
MBCQ ( —— )
产品货号. M22973 CAS No. 150450-53-6
MBCQ 是一种 cGMP 特异性磷酸二酯酶 PDE5 抑制剂。MBCQ 是一种选择性 PDE5 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥226 | 有现货 |
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| 5MG | ￥377 | 有现货 |
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| 10MG | ￥695 | 有现货 |
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| 25MG | ￥1376 | 有现货 |
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| 50MG | ￥2055 | 有现货 |
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| 100MG | ￥2853 | 有现货 |
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| 200MG | ￥3987 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥443 | 有现货 |
|
生物学信息
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产品名称MBCQ
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述MBCQ 是一种 cGMP 特异性磷酸二酯酶 PDE5 抑制剂。MBCQ 是一种选择性 PDE5 抑制剂。
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产品描述MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
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体外实验MBCQ (compound 3d) induces relaxation of isolated porcine coronary arteries precontracted with prostaglandin F2α (PGF2α; EC50=190 nM). MBCQ (0.01-10 μM; 10 min) inhibits Carbachol (10 μM)-induced contractions in a concentration-dependent manner in rat ileal smooth muscle.
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体内实验——
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同义词——
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通路Angiogenesis
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靶点PDE
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受体PDE5
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研究领域——
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适应症——
化学信息
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CAS Number150450-53-6
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分子量313.74
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分子式C16H12ClN3O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (318.74 mM)
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SMILESClC1=CC2=C(N=CN=C2NCC3=CC=C(OCO4)C4=C3)C=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Macpherson J D , Gillespie T D , Dunkerley H A , et al. Inhibition of Phosphodiesterase 5 Selectively Reverses Nitrate Tolerance in the Venous Circulation[J]. Journal of Pharmacology & Experimental Therapeutics, 2006, 317(1):188.
产品手册
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