1-Methylhistamine dihydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

1-甲基组胺二盐酸盐是组氨酸代谢途径中组胺N-甲基转移酶的主要代谢产物。它已被用作阿尔茨海默病患者以及患有嗜睡症和其他神经系统疾病的患者大脑中组胺能系统活动的生物标志物。

1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism.?It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer's disease patients as well as those with hypersomnia and other neurological conditions.

——

——

——

Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

——

——

6481-48-7

198.09

C6H13Cl2N3?

>98% (HPLC)

In Vitro:?H2O : 62.5 mg/mL (315.51 mM)

NCCC1=CN(C)C=N1.[H]Cl.[H]Cl

——

(-20℃)

With Ice Pack

≥ 2 years