Speract TFA(76901-59-2(free base))

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Speract TFA 是一种海胆卵肽，可调节精子活力，同时刺激精子线粒体代谢。Speract 刺激精子可使线粒体去极化并增加 NADH 水平。令人惊讶的是，这些反应与外部Ca(2+)无关，并且是由于speract诱导的细胞内pH(pHi)增加所致。

Speract TFA is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.The stimulation of sperm with speract depolarizes the mitochondrion and increases the levels of NADH.?Surprisingly, these responses are independent of external Ca(2+) and are due to the increase in intracellular pH (pHi) induced by speract.?Speract, by regulating pHi, in addition to [Ca(2+)]i, may finely modulate mitochondrial metabolism to control motility and ensure that sperm reach the egg and fertilize it.

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Others

Other Targets

Others

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891.92

C38H57N11O14

>98% (HPLC)

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OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years