Nourseothricin sulfate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

诺尔丝菌素硫酸盐是一种广谱抗生素，抑制原核细胞中的蛋白质生物合成，并强烈抑制真核生物（如真菌）的生长。诺尔丝菌素的肾脏处理在各种实验条件下的肾皮质切片实验中进行了表征。

Nourseothricin sulfate is a broad-spectrum antibiotic,and inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi .Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions.?Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin.?There is a high degree of accumulation of Nourseothricin in renal cortical slices.?In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation.?Age dependent differences in Nourseothricin accumulation does not exist.

——

——

Streptothricin sulfate

GPCR/G Protein

Antibacterial

Bacterial

——

——

96736-11-7

1359.47

C50H94N20O22S

>98% (HPLC)

H2O:250 mg/mL (183.90 mM; Need ultrasonic)

O=S(=O)(O)O.NCCC[C@H](N)CC(=O)N[C@@H]3[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)O[C@H]3NC1=N[C@@H]2C(=O)NC[C@@H](O)[C@H]2N1.NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)N[C@@H]3[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)O[C@H]3NC=1N[C@@H]2[C@H](O)CNC(=O)[C@H]2N=1

——

(-20℃)

With Ice Pack

≥ 2 years