FOY 251

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

FOY 251 是一种蛋白酶抑制剂，也是一种抗蛋白水解活性代谢物卡莫司特。FOY-251 是卡莫司他甲磺酸盐的活性代谢物，对小鼠皮质集合管细胞系（M-1 细胞）中的钠转运和小鼠血压有影响。

FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.?Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro.

FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells.FOY-251 inhibits the proteolytic activity of prostasin.

——

——

Others

Other Targets

proteinase

——

——

71079-09-9

409.41

C17H19N3O7S

>98% (HPLC)

In Vitro:?DMSO : 20 mg/mL (48.85 mMul)

CS(O)(=O)=O.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(O)=O)cc1

——

(-20℃)

With Ice Pack

≥ 2 years