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Benzonatate
CAS No. 104-31-4
Benzonatate ( —— )
产品货号. M22185 CAS No. 104-31-4
苯佐那酯是钠通道蛋白的拮抗剂。含有 9-乙氧基成分的苯佐那酯组分对 Na(+) 电流的抑制最为有效。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥394 | 有现货 |
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| 10MG | ￥637 | 有现货 |
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| 25MG | ￥1253 | 有现货 |
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| 50MG | ￥1786 | 有现货 |
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| 100MG | ￥3038 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥528 | 有现货 |
|
生物学信息
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产品名称Benzonatate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述苯佐那酯是钠通道蛋白的拮抗剂。含有 9-乙氧基成分的苯佐那酯组分对 Na(+) 电流的抑制最为有效。
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产品描述Benzonatate is an antagonist of sodium channel protein.Na(+) currents are inhibited most potently by a benzonatate fraction containing the 9-ethoxy component.?Detectable effects of benzonatate occur at concentrations as low as 0.3 μM, which has been reported in humans. benzonatate has local anesthetic-like effects on voltage-gated sodium channels, including Nav1.7, which is a possible mechanism for cough suppression by the drug.
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体外实验——
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体内实验——
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体sodium channel
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研究领域——
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适应症——
化学信息
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CAS Number104-31-4
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分子量603.75
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分子式C30H53NO11
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (165.63 mM)
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SMILESCCCCNc1ccc(cc1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Evans M S , Maglinger G B , Fletcher A M , et al. Benzonatate inhibition of voltage-gated sodium currents[J]. Neuropharmacology, 2016, 101:179.
