6''-O-Malonylgenistin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

6''-O-Malonylgenistin 具有保肝活性。使用两步梯度溶剂系统在 C 18 反相柱上分析大豆样品中的异黄酮浓度。

6''-O-Malonylgenistin possesses a hepatoprotective activity.The isoflavone concentration in soybean samples was analyzed on a C 18 reverse-phase column using a two-step gradient solvent system. Producing soybean hydrolysate led to a nearly 40% loss of isoflavones compared with the original soybean flour, but the isoflavone composition did not change and the dominant isoflavone chemicals remained as 6''-O-Malonylgenistin and 6''-O-malonyldaidzin. Ion exchange chromatography affected significantly both the content and the composition of the isoflavones. The dominant isoflavones in the ion-exchanged fraction were aglycones and nonacylated isoflavones, accounting for 95.8% of the total amount of 987.7 microg/g. It was calculated that the isoflavone content in the soybean ACE inhibitory peptide fraction was 25 times less than the minimal effective isoflavone dose reported. In vitro study also showed that adding isoflavones into both soybean flour hydrolysate and soybean ACE inhibitory peptide samples to a concentration of as high as 31.5% (w/w) did not affect ACE inhibitory activity (IC 50 values).

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Others

Other Targets

Others

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51011-05-3

518.42

C24H22O13

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (192.89 mM)

O[C@@H]1[C@@H](COC(=O)CC(O)=O)O[C@@H](Oc2cc(O)c3c(c2)occ(-c2ccc(O)cc2)c3=O)[C@H](O)[C@H]1O

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(-20℃)

With Ice Pack

≥ 2 years