3-O-Acetyl-16 alpha-hydroxytrametenolic acid ( —— )

产品货号. M22054 CAS No. 168293-13-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

3-O-Acetyl-16 alpha-hydroxytrametenolic acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

3-O-Acetyl-16 α-羟基四烯醇酸对 AAPH 诱导的红细胞溶血具有抑制活性，对 12-O-tetradecanoylphorbol-13-acetate 诱导的小鼠炎症有很强的抑制活性。
产品描述

3-O-Acetyl-16 alpha-hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.In this study, tests were carried out to identify the main ingredient of Hoelen that has the scavenging effect on free-radicals. Triterpene carboxylic acids isolated from the methanol extract of Hoelen, i.e. pachymic acid, polyporenic acid, 3-epidehydrotumulosic acid, 3beta-hydroxylanosta-7,9(11), 24-trien-21-oic acid and 3-O-Acetyl-16 alpha-hydroxytrametenolic acid, were found to have inhibitory activities against AAPH-induced lysis of red blood cells.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Immunology & Inflammation related
研究领域

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适应症

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CAS Number

168293-13-8
分子量

514.8
分子式

C32H50O5
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 7.14 mg/mL (13.87 mM)
SMILES

[H][C@]1([C@@H](CCC=C(C)C)C(O)=O)[C@H](O)C[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](OC(C)=O)C(C)(C)[C@]1([H])CC3
化学全称

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1.Inhibitory effects of triterpenes isolated from Hoelen on free radical-induced lysis of red blood cells.Phytother Res. 2003 Feb;17(2):160-2.

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