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Centhaquine

CAS No. 57961-90-7

Centhaquine ( Centhaquine,PMZ-2010 )

产品货号. M22037 CAS No. 57961-90-7

Centhaquine 是一种肾上腺素能受体,可用于治疗术后疼痛和低血容量性休克的复苏。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥549 有现货
10MG ¥825 有现货
25MG ¥1609 有现货
50MG ¥2409 有现货
100MG ¥3528 有现货
200MG ¥5031 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥605 有现货

生物学信息

  • 产品名称
    Centhaquine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Centhaquine 是一种肾上腺素能受体,可用于治疗术后疼痛和低血容量性休克的复苏。
  • 产品描述
    Centhaquine is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock.(In Vivo):Centhaquine (Centhaquin) (intravenous injection, 0.01-1.0 mg/kg; intraduodenal administration 1.0-2.5 mg/kg) lowers the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner.Centhaquine (Centhaquin) (intravertebral arterial injection; 5-10 μg) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle causes hypotension and bradycardia as well as reduced the excitability of the vasomotor loci.Centhaquine (Centhaquin;PMZ-2010) (intravenous administration; 0.015mg/kg) can attenuate the deleterious effects of catecholamines, improving both the macro- and microcirculation during CPR.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    Centhaquine,PMZ-2010
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Others
  • 适应症
    Hypovolemic Shock

化学信息

  • CAS Number
    57961-90-7
  • 分子量
    331.45
  • 分子式
    C22H25N3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:60 mg/mL (181.02 mM; Need ultrasonic)
  • SMILES
    CC1=CC(=CC=C1)N1CCN(CCC2=NC3=CC=CC=C3C=C2)CC1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Papalexopoulou K, et al. Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.Heart Lung Circ. 2017 Aug;26(8):856-863.
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