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Gartanin
CAS No. 33390-42-0
Gartanin ( —— )
产品货号. M21922 CAS No. 33390-42-0
Gartanin 是山竹的天然黄酮，具有抗氧化、抗炎、抗真菌、神经保护和抗肿瘤特性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2261 | 有现货 |
|
| 10MG | ￥3354 | 有现货 |
|
| 25MG | ￥5329 | 有现货 |
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| 50MG | ￥7282 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥2356 | 有现货 |
|
生物学信息
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产品名称Gartanin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Gartanin 是山竹的天然黄酮，具有抗氧化、抗炎、抗真菌、神经保护和抗肿瘤特性。
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产品描述Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells.Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways.Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells.(In Vitro):Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways .Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells .
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体外实验Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways .Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells .
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域——
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适应症——
化学信息
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CAS Number33390-42-0
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分子量396.43
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分子式C??H??O?
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (315.31 mM)
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SMILESO=C1C2=C(OC3=C(O)C=CC(O)=C13)C(C/C=C(C)\C)=C(O)C(C/C=C(C)/C)=C2O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Gao XY, et al. Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK. Neurochem Res. 2016 Sep;41(9):2267-77.
2. Kim MO, et al. Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis. Oncol Rep. 2015 Jul;34(1):139-46.
产品手册
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