Biotin-PEG4-N3

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Biotin-PEG3-azide 是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。

Biotin-C2-PEG3-azide is a biotin with the azide tag, it can be conjugated to antiviral inhibitors, for example, RYL-634, which shows excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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PROTACs

PROTAC

PEGs

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875770-34-6

444.55

C??H??N?O?S

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (224.95 mM)

O=C(NCCOCCOCCOCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

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(-20℃)

With Ice Pack

≥ 2 years