The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.

VU625 (VU007625) is a selective and potent AeKir1 inhibitor (IC50: 96.8 nM) that acts as a mosquito killer and inhibits AeKir1-mediated currents.

CP-24879 盐酸盐是一种 Δ5D/Δ6D 双抑制剂，可显着减少肝细胞内脂质积累和炎症损伤。 CP-24879 盐酸盐在 fat-1 和 ω-3 处理的肝细胞中表现出优异的抗脂肪变性和抗炎作用。