Thiazolyl Blue ( —— )

产品货号. M21733 CAS No. 298-93-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Thiazolyl Blue
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

噻唑蓝 (MTT) 是一种广泛用于测量细胞增殖的比色剂。噻唑蓝 (MTT) 在活细胞中从黄色还原为紫色甲臜。
产品描述

Thiazolyl Blue (MTT) is used in conjunction with rhodamine B to measure mitochondrial membrane potential. Thiazolyl Blue-formazan is generated in mitochondria acts as a fluorescence quencher for rhodamine that distributes across membranes of viable cells according to membrane potential. In the absence of mPMS, cellular reduction of Thiazolyl Blue is strong. Thiazolyl Blue is membrane-impermeable when incorporated into large unilamellar liposomes, and therefore it is taken up by cells via endocytosis.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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CAS Number

298-93-1
分子量

414.32
分子式

C??H??BrN?S
纯度

>98% (HPLC)
溶解度

DMSO : 25 mg/mL (60.34 mM; Need ultrasonic);H2O : 0.88 mg/mL (2.12 mM; Need ultrasonic and warming)
SMILES

CC1=C(C)N=C(N2N=C(C3=CC=CC=C3)N=[N+]2C4=CC=CC=C4)S1.[Br-]
化学全称

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1. Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52.

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