Rhodionin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Rhodionin 是从红景天 (Rhodiola crenulata) 的根中分离的，一种特异性非竞争性细胞色素 P450 2D6 抑制剂，IC50 为 0.761 μM，Ki 为 0.769 μM。Rhodionin 有效的，剂量依赖性抑制乙酰胆碱酯酶 (AChE)，IC50 范围为 57.50 至 2.43 μg/mL。Rhodionin 具有有效的 DPPH 自由基清除活性，IC50 为 19.49 μM。

Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of the postprandial blood triglyceride level suggests that they may be to the treatment of lifestyle-related diseases such as hyperlipidemia and exogeneous obesity and to health foods.

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Metabolic Enzyme/Protease

P450

CYP450

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85571-15-9

448.38

C21H20O11

>98% (HPLC)

In Vitro:?DMSO : 16.67 mg/mL (37.18 mM)

C[C@@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@H]1Oc(cc(c(C1=O)c2OC(c(cc3)ccc3O)=C1O)O)c2O

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(-20℃)

With Ice Pack

≥ 2 years