3-Methyl-L-histidine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

3-甲基组氨酸属于一类称为组氨酸及其衍生物的有机化合物。组氨酸及其衍生物是含有半胱氨酸或其衍生物的化合物，其由半胱氨酸在氨基或羧基上的反应或由杂原子取代甘氨酸的任何氢而产生。

3-Methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing cysteine or a derivative thereof resulting from reaction of cysteine at the amino group or the carboxy group or from the replacement of any hydrogen of glycine by a heteroatom. It is also a biomarker for the consumption of soy products. 3-Methylhistidine is a very strong basic compound (based on its pKa). 3-Methylhistidine exists in all eukaryotes ranging from yeast to humans. In humans 3-methylhistidine is involved in methylhistidine metabolism. 3-Methylhistidine with regard to humans has been found to be associated with several diseases such as diabetes mellitus type 2 eosinophilic esophagitis and kidney disease; 3-methylhistidine has also been linked to the inborn metabolic disorder propionic acidemia. The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a product of peptide bond synthesis and methylation of actin and myosin. 3-Methylhistidine is a biomarker for meat consumption especially chicken.

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Proteasome/Ubiquitin

Endogenous Metabolite

Human Endogenous Metabolite

Metabolic Disease

Intestinal Diseases

368-16-1

169.18

C7H11N3O2

>98% (HPLC)

In Vitro:?H2O : 100 mg/mL (591.09 mM)

Cn1c(C[C@@H](C(O)=O)N)cnc1

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(-20℃)

With Ice Pack

≥ 2 years