573'4'-Tetramethoxyflavone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

5,7,3',4'-四甲氧基黄酮是从奇异果中分离出来的主要多甲氧基黄酮 (PMF) 之一，具有多种生物活性，包括抗真菌、抗疟疾、抗分枝杆菌和抗炎活性。 5,7,3',4'-四甲氧基黄酮通过靶向 β-连环蛋白信号传导表现出软骨保护活性。

573'4'-Tetramethoxyflavone one of the major polymethoxyflavones (PMFs) isolated from M. exotica possesses various bioactivities including anti-fungal anti-malarial anti-mycobacterial and anti-inflammatory activities. 573'4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling.

Cell Line:Concentration:Incubation Time:Result:Western Blot Analysis Cell Line:Chondrocytes Concentration:5-20 μg/mL Incubation Time:4 h Result:Increased the protein level of Bcl-2 and XBP1s.Decreased the expression of pro-apoptotic factors CHOP/caspase-3 and stress kinase JNK.

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Microbiology/Virology

Antifungal

Antifungal|Antibacterial

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855-97-0

342.35

C19H18O6

>98% (HPLC)

DMSO:8.33 mg/mL (24.33 mM)

COc(cc1OC)cc(OC(c(cc2)cc(OC)c2OC)=C2)c1C2=O

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(-20℃)

With Ice Pack

≥ 2 years